pa:(CHOI, Jae, Sue)
4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME
PCT/KR2002/001595
[CHOI, Won, Chul, SUH, Hongsuk, CHOI, Jae, Sue, KIM, Dae-Duk, SONG, Yeong-Ok, KIM, Jae-Kon]
#103-1908 Hyundai Apt. Gaegeum-3-dong, Busan Jin-gu 614-113 Busan-si;3rd Floor, Yaelim Bldg. 688-2 Yoksam-dong, Gangnam-gu 135-080 Seoul;#112-502 Daewoo Apt. 244-7 Bugok-2-dong, Geumjung-gu 609-322 Busan-si;#105-1502 Hwamok Apt., Haewoondae-gu 612-030 Busan-si;#106-1606 Gyoungnam Hanshin Apt. Bugok-dong, Geumjung-gu 609-322 Busan-si;#101-1404 Gyoungdong Apt. Chungryong-dong, Geumjung-gu 609-350 Busan-si;131-6 Suh-3-dong, Geumjung-gu 612-789 Busan-si
The present invention relates to 4-[(alkylsulfanyl)methyl]-1, 2-benzenediol derivative, preparation method thereof and antioxidant containing the same. More particularly, 4-[(alkylsulfanyl)methyl]-1, 2-benzenediol derivative following Formula (1) can inhibit generation of melanin due to its excellent antioxidant activity and can regulate blood cholesterol level by repressing oxidation of low density lipoprotein. Accordingly, the present invention can be useful for treatments of arteriosclerosis and skin deposit by reactive oxygen species.
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R-7-(3-AMINOMETHYL-4-METHOXYIMINO-3-METHYL-PYRROLIDIN-1-YL)-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-[1,8]NAPHTHYRIDINE-3-CARBOXYLIC ACID AND L-ASPARTIC ACID SALT, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME FOR ANTIMICROBIAL
PCT/KR2010/004938
[CHOI, Dong Rack, YANG, Jin, YOON, Sue Hye, PYUN, Sung Jae, KIM, Seung Hwan, SEONG, Seung-Kyoo, RYU, Jei Man]
1004Ho Byucksan Digital Valley 9 Mullae-dong 5-ga, Yeongdeungpo-gu Seoul 150-095;#311-201 Dongwon Royaldeuk Apt., Bojong-dong, Giheung-gu, Yongin-si Gyunggi-do 446-976;#201-302 Shinil Apt., Yeongdeok-dong, Giheung-gu, Yongin-si Gyunggi-do 446-741;#125-504 Cheoncheon Prugio Apt., Cheoncheon-dong, Jangan-gu, Suwon-si Gyunggi-do 440-710;#108-2402 Hanmaul Apt., Gaebong-dong, Guro-gu Seoul 152-752;#143-1404 Jinheung Apt., Hwaseo-2dong, Paldal-gu, Suwon-si Gyunggi-do 442-872;#110-1102 Kumho Apt., Dongchun-3dong, Yeonsu-gu Incheon 406-775;#207-101 Eunhasu Apt., 1103 Buheung-dong, Dongan-gu, Anyang-si Gyunggi-do 431-817
Disclosed herein are R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial. Because the R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt is more soluble and less toxic and has less side effects as an antimicrobial agent than hydrochloride and the other salts (D-aspartate and phosphate) conventionally used, the salt may be useful for oral and injectable administration.
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CELL GROWTH STIMULATING COMPOSITIONS CONTAINING ALOESIN
PCT/KR1995/000016
[KIM, Kyeong, Ho, PARK, Jeong, Hill, SUNG, Chung, Ki, KIM, Jin, Woong, CHOI, Jae, Sue, LEE, Seung, Ki, KIM, Yeong, Shik, SON, Byeong, Hwa, CHUNG, Myung, Hee, PARK, Young, In, KIM, Kyu, Won, LEE, Chong, Kil]
815-4, Yeoksam-dong Kangnam-ku Seoul 138-080;6-1103, Kumho-town Oneui-dong Kangwondo Choonchun 100-190;Professor Apartment of Seoul National University Bongchun 7-dong Kwanak-ku Seoul 151-057;108-701, Moa-town Choongheung 2-dong Puk-ku Kwangju 500-042;12-303 Samho Apartment 1301-6, Seocho-dong Seocho-ku Seoul 137-070;285-10, Youngju 2-dong Joong-ku Pusan 600-112;34-12, Banpo-dong Seocho-ku Seoul 137-040;Na-205 Professor Apartment of Seoul National University Bongchun 7-dong Kwanak-ku Seoul 151-057;342-18, Yeonsan 8-dong Dongrae-ku Pusan 607-088;7th Apartment, 302-806, Hanshin Chamwon-dong Seocho-ku Seoul 137-030;106-102 Hyundai Apartment 653, Kaepo-dong Kangnam-ku Seoul 135-240;601-607 Greencore Apartment Manduk 3-dong Puk-ku Pusan 616-113;Apartment #101 San 12-5, Kaeshin-dong Chungchongbukdo Chungjoo 360-240
The present invention relates to a cell growth stimulating composition containing aloesin as an active ingredient. More specifically, the present invention relates to a composition for stimulating cell growth, especially for stimulating epidermal cells and hepatic cells, which contains aloesin as an active ingredient. Aloesin is a component of Aloe vera, for which an effect for blocking ultraviolet ray from skin and an activity as mushroom tyrosinase inhibitor have been disclosed in the prior art. However, accordint to the present invention, it has now been identified that aloesin has the novel pharmacological use as a cell growth stimulating agent which has never been disclosed in the prior art.
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System for monitoring haze of a photomask
US12588490
[Dong-gun Lee, Seong-sue Kim, Jae-Hyuck Choi, Jin-sik Jung]
KR Hwaseong-si
A system for monitoring haze of a photomask includes an installation unit in which a photomask is mounted, a light emission unit emitting a light beam to the photomask installed on the installation unit, a detection unit detecting a diffraction pattern of the light beam emitted by the light emission unit and passed through the photomask, and an analysis unit analyzing the diffraction pattern detected by the detection unit.
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R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial
US13387080
[Dong Rack Choi, Jin Yang, Sue Hye Yoon, Sung Jae Pyun, Seung Hwan Kim, Seung-Kyoo Seong, Jei Man Ryu]
KR Yongin-si
Disclosed herein are R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial. Because the R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl) -1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt is more soluble and less toxic and has less side effects as an antimicrobial agent than hydrochloride and the other salts (D-aspartate and phosphate) conventionally used, the salt may be useful for oral and injectable administration.
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System for monitoring haze of a photomask
US12588490
[Dong-gun Lee, Seong-sue Kim, Jae-Hyuck Choi, Jin-sik Jung]
KR Hwaseong-si
A system for monitoring haze of a photomask includes an installation unit in which a photomask is mounted, a light emission unit emitting a light beam to the photomask installed on the installation unit, a detection unit detecting a diffraction pattern of the light beam emitted by the light emission unit and passed through the photomask, and an analysis unit analyzing the diffraction pattern detected by the detection unit.
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