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[SOYAMA YOSHIKAZU, YOSHIKAZU SOYAMA KAZUNORI YAMAZAKI ET CHIGUSA KITAMURA, YAMAZAKI KAZUNORI, KITAMURA CHIGUSA] JP;

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JP;

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[Nishino Chikao(c/o Shieseido Research Center(2) 2-12-1 Fukuura, Kanazawa-ku,Yokohama-shi, Kanagawa 236), Sato Fumitaka(c/o Shiseido Research Center(1) 1050 Nippa-cho, Kohoku-ku,Yokohama-shi, kanagawa 223), Uetake Tomohiro(10-2 Sotokanda 4-chome, Chiyoda-ku,Tokyo 101), Fukunishi Hirotada(c/o Shiseido Research Center(1) 1050 Nippa-cho, Kohoku-ku,Yokohama-shi, Kanagawa 223), Kojima Nao(c/o Shiseido Co., Ltd. 5-5 Ginza 7-chome, Chuo-ku,Tokyo 104-10)] A pyridine derivative or a salt thereof expressed by the following formula 1: ##STR1## wherein W represents a group expressed by the following formula 2 or formula 3; ##STR2## wherein R.sub.1 represents an alkenyloxy group; n represents 1 or 2; Ra represents a lower alkyl group; and Rb represents a halogen atom; and wherein each of R.sub.2 and R.sub.3 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, or halogenated alkyl group; Y represents a group expressed by --S--, --NH-- or --CONH--; m represents an integer of 0 to 2; and p represents 0 or 1. The pyridine derivative has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulcers.

[Miyazawa, Kiyoshi, Tomita, Kenichi, Saito, Yoshinobu, c/o Shiseido Honey-Cake, Kishi, Nobuyuki, c/o Shiseido Honey-Cake, Kurimoto, Hirokatsu, c/o Shiseido Honey-Cake, Itoh, Hajimu, c/o Shiseido Honey-Cake, Nishina, Tetsuo, c/o Shiseido Honey-Cake] 7-5-5, Ginza, Chuo-ku Tokyo 104-10, JP